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Identification of STEMI Equivalent ECG Patterns

On completing this course you will identify ST elevation myocardial infraction (STEMI) equivalent ECG patterns in cases of suspected acute myocardial infarction. In addition, you will identify the ECG findings associated with Wellens Syndrome.

2.0 x AMA PRA Category 1 Credits™
Available on the Pro Plan

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Overview

Patients presenting with significant new-onset ST elevation on their ECG in the setting of acute myocardial infarction are considered candidates for emergent reperfusion therapy. Four ECG patterns observed in acute myocardial infarction, in which ST elevation is absent, are now also considered an indication for emergent reperfusion therapy. The four ‘STEMI equivalent’ ECG patterns are, 1) left bundle branch block satisfying the Smith modified Sgarbossa criteria, 2) acute posterior myocardial infarction 3) hyperacute T wave change and 4) the presence of de Winter T waves on the ECG. Although not STEMI equivalent, a fifth ECG pattern is associated with imminent coronary artery occlusion (Wellens syndrome) and mandates early intervention. On completing this course, the practitioner will identify STEMI equivalent ECG patterns and the ECG changes associated with Wellens Syndrome.

Faculty

Planner and Author: Dr John Seery MB PhD

  • Consultant Physician at St. Vincent's University Hospital, Dublin, Ireland
  • Lecturer at the School of Medicine and Medical Science, University College Dublin, Ireland
  • Studied medicine at the University of Cambridge, United Kingdom
  • A Natural Sciences graduate of Trinity College Dublin, Ireland
  • PhD in Cell Biology from University College London, United Kingdom

Planner: Dr Karen Strahan PhD (University of Cambridge), Head of Editorial

Planner: Tommy O'Sullivan, CME Manager

Estimated Time to Complete

2.0 hours

Target Audience

Select Target Audience(s)

- Physicians

- Nurses

- Nurse Practitioners

- Physician Assistants

- Paramedics

Learning Objectives

Upon successful completion of this activity, you will be able to:

  • Explain the historical origin of ‘STEMI criteria’
  • Explain the term ‘STEMI equivalent ECG pattern’
  • Explain the clinical significance of STEMI equivalent patterns on the ECG of patients presenting with suspected acute myocardial infarction
  • Apply and interpret the Smith modified Sgarbossa criteria in cases of suspected acute myocardial infarction presenting with left bundle branch block on their ECG
  • Identify the ECG changes characteristic of posterior myocardial infarction
  • Identify hyperacute T wave change on the ECG of patients presenting with suspected acute myocardial infarction
  • Identify de Winter T waves on the ECG of patients presenting with suspected acute myocardial infarction
  • Identify and interpret the ECG findings associated with Wellens syndrome
  • Distinguish normal variant prominent T waves from hyperacute T waves in patients presenting with chest pain

Course Content

  • Introduction
  • Before we begin Key terms explained
  • Posterior Myocardial Infarction ECG Findings
  • Identifying Left Bundle Branch Block on the ECG
  • Smith modified Sgarbossa Criteria
  • The Smith modified Sgarbossa Criteria Case Study
  • The Chest Leads Normal Findings
  • Identification of Hyperacute T Waves on the ECG
  • Prominent T Waves in Healthy Adults
  • de Winter T Waves
  • Wellens Syndrome ECG Findings
  • Quiz
  • Quiz Explanation - Q1/Q2
  • Quiz Explanation - Q3
  • Quiz Explanation - Q4/Q5

Release date

30-JUL-2026

Expiration date

30-JUL-2029

Instructions for Participation

Participants must complete the online activity during the valid period as noted above.

Follow these steps:

  1. View videos in sequence
  2. Read the papers on the Essential Reading List
  3. Complete quiz
  4. View and complete post quiz videos to support learning outcomes and objectives
  5. Complete the activity evaluation form to provide feedback for continuing education purposes and for the development of future activities
  6. Download the Certificate of Completion

Relevant Financial Disclosures

Planners and faculty for this activity have no relevant financial relationships with commercial interests to disclose.

Bibliography

Johnston FD. Frank Norman Wilson: November 19, 1890-September 11, 1952. Circulation. 1952;6(5):641-2.

PMID: 12988344 DOI: 10.1161/01.cir.6.5.641

 

Rautaharju PM et al. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol. 2009;53(11):982-91.

PMID: 19281931 DOI: 10.1016/j.jacc.2008.12.014

 

DeWood, MA et al. Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction. N Engl J Med 1980;303(16):897-902.

PMID: 7412821 DOI: 10.1056/NEJM198010163031601

 

DeWood MA et al. Coronary Arteriographic Findings Soon after non-Q-Wave Myocardial Infarction. N Engl J Med  1986; 315(7):417-23.

PMID: 3736619 DOI: 10.1056/NEJM198608143150703

 

No authors listed. Effectiveness of intravenous thrombolytic treatment in acute myocardial infarction. Gruppo Italiano per lo Studio della Streptochinasi nell'Infarto Miocardico (GISSI). Lancet . 1986;1(8478):397-402.

PMID: 2868337

 

No authors listed. Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group. Lancet 1988;2(8607):349-60.

PMID: 2899772

GUSTO investigators. An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med. 1993;329(10):673-82.

PMID: 8204123 DOI: 10.1056/NEJM199309023291001

 

GUSTO investigators. A clinical trial comparing primary coronary angioplasty with tissue plasminogen activator for acute myocardial infarction. N Engl J Med. 1997;336(23):1621-8.

PMID: 9173270 DOI: 10.1056/NEJM199706053362301

 

Chapman GD et al. Minimizing the risk of inappropriately administering thrombolytic therapy (Thrombolysis and Angioplasty in Myocardial Infarction [TAMI] study group). Am J Cardiol. 1993;71(10):783-7.

PMID: 8456754 DOI: 10.1016/0002-9149(93)90824-v

 

Wang TY et al. Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non-ST-elevation acute coronary syndromes undergoing diagnostic angiography. Am Heart J. 2009;157(4):716-23.

PMID: 19332201 DOI: 10.1016/j.ahj.2009.01.004

 

Kontos MC et al. 2022 ACC Expert Consensus Decision Pathway on the Evaluation and Disposition of Acute Chest Pain in the Emergency Department. A report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2022;80:1925-60.

PMID: 36241466 DOI: 10.1016/j.jacc.2022.08.750

 

Rao SV et al. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2025 Apr;151(13):e771-e862.

PMID: 40014670 DOI: 10.1161/CIR.0000000000001309

 

Thygesen K, Alpert JS, Jaffe AS et al. Fourth Universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018;72;2231-2264.

PMID: 30153967 DOI: 10.1016/j.jacc.2018.08.1038

 

Rokos IC, French WJ, Mattu A et al. Appropriate cath lab activation: optimizing electrocardiogram interpretation and clinical decision-making for acute ST-elevation myocardial infarction.  Am Heart J. 2010;160(6):995-1003, 1003.e1-8.

PMID: 21146650 DOI: 10.1016/j.ahj.2010.08.011

 

Wang K et al. ST-Segment Elevation in Conditions Other Than Acute Myocardial Infarction. N Eng J Med. 2003;349(22):2128-35.

PMID: 14645641 DOI: 10.1056/NEJMra022580

 

McLaren J et al. From ST-Segment Elevation MI to Occlusion MI: The New Paradigm Shift in Acute Myocardial Infarction. JACC. 2024;3(11):101314

PMID: 39435181 DOI: 10.1016/j.jacadv.2024.101314

 

Khan JN et al. Posterior myocardial infarction: are we failing to diagnose this?

Emerg Med J. 2012; 29(1):15-8.

PMID: 20961938 DOI: 10.1136/emj.2010.099861

 

Dunn WJ et al. The electrocardiogram in infarction of the lateral wall of the left ventricle; a clinicopathological study. Circulation. 1956;14(4 Part 1):540-55.

PMID: 13365061 DOI: 10.1161/01.cir.14.4.540

 

Perloff JK.The recognition of strictly posterior myocardial infarction by conventional scalar electrocardiography. Circulation. 1964:30:706-18.

PMID: 14226169 DOI: 10.1161/01.cir.30.5.706

Bayés de Luna A et al. Concordance of electrocardiographic patterns and healed myocardial infarction location detected by cardiovascular magnetic resonance. Am J Cardiol. 2006;97(4):443-51.

PMID: 16461034 DOI: 10.1016/j.amjcard.2005.08.068

 

Bayés de Luna A et al. A new terminology for left ventricular walls and location of myocardial infarcts that present Q wave based on the standard of cardiac magnetic resonance imaging: a statement for healthcare professionals from a committee appointed by the International Society for Holter and Noninvasive Electrocardiography. Circulation 2006;114(16):1755-60.

PMID: 17043179 DOI: 10.1161/CIRCULATIONAHA.106.624924

 

Garcia-Cosío F. Posterior myocardial infarction is real. Rev Esp Cardiol. 2008 Apr;61(4):430-1; author reply 431-2.

PMID: 18405526 (link to letter and reply)

Di Diego JM & Antzelevitch C.   Acute Myocardial Ischemia: Cellular Mechanisms Underlying ST Segment Elevation. J Electrocardiol. 2014 Feb 25;47(4):486–490.

PMID: 24742586

 

 

Rinta-Kiikka I et al. Correlation of electrocardiogram and regional cardiac magnetic resonance imaging findings in ST-elevation myocardial infarction: a literature review. Ann Noninvasive Electrocardiol. 2014;19(6):509-23.

PMID: 25201553 DOI: 10.1111/anec.12210

 

Sgarbossa EB et al. Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators. N Engl J Med 1996; 334(8):481-7.

PMID: 8559200 DOI: 10.1056/NEJM199602223340801

 

 

Smith SW et al. Diagnosis of ST-elevation myocardial infarction in the presence of left bundle branch block with the ST-elevation to S-wave ratio in a modified Sgarbossa rule. Ann Emerg Med. 2012;60(6):766-76.

PMID: 22939607 DOI: 10.1016/j.annemergmed.2012.07.119

 

Willems JL et al. Criteria for intraventricular conduction disturbances and pre-excitation. J Am Coll Cardiol. 1985 5(6):1261-75.

PMID: 3889097 DOI: 10.1016/s0735-1097(85)80335-1

 

Pérez-Riera AR et al. R-Peak Time: An Electrocardiographic Parameter with Multiple Clinical Application. Ann Noninvasive Electrocardiol. 2016 21(1):10-9.

PMID: 26523751 DOI: 10.1111/anec.12323

Dressler W & Roesler H. High T waves in the earliest stage of myocardial infarction. Am Heart J. 1947;34(5):627-645.

PMID: 20268227 DOI: 10.1016/0002-8703(47)90343-8

 

Somers MP et al. The prominent T wave: electrocardiographic differential diagnosis.

Am J Emerg Med. 2002;20(3):243-51.

PMID: 11992348 DOI: 10.1053/ajem.2002.32630

 

Kenigsberg DN et al. Prolongation of the QTc interval is seen uniformly during early transmural ischemia. J Am Coll Cardiol. 2007;49(12):1299-305.

PMID: 17394962 DOI: 10.1016/j.jacc.2006.11.035

 

Warren SG & Wagner GS. The STAFF studies of the first 5 minutes of percutaneous coronary angioplasty balloon occlusion in man. 2014. 47(4):402-7.

PMID: 24928432 DOI: 10.1016/j.jelectrocard.2014.04.011

 

Pessah MA et al. Early ischemic ST-segment and T-wave changes during balloon angioplasty. J Electrocardiol. 2022;73:87-95.

PMID: 35738147 DOI: 10.1016/j.jelectrocard.2022.06.003

 

Meyers HP, Simancik F, Hermann R et al. Hyperacute T Waves Are Specific for Occlusion Myocardial Infarction, Even Without Diagnostic ST-Segment Elevation. JACC. 2025;10(2):102120.

PMID: 40892623 DOI: 10.1016/j.jacadv.2025.102120

 

Koechlin L et al. Hyperacute T Wave in the Early Diagnosis of Acute Myocardial Infarction.

Ann Emerg Med. 2023;82(2):194-202.

PMID: 36774205 DOI: 10.1016/j.annemergmed.2022.12.003

 

Smith SW & Meyers HP. Hyperacute T-waves Can Be a Useful Sign of Occlusion Myocardial Infarction if Appropriately Defined. Ann Emerg Med. 2023;82(2):203-206.

PMID: 36872197 DOI: 10.1016/j.annemergmed.2023.01.011

 

Klis M. Early repolarization – benign or early sign? British Cardiovascular Society Editorial. April 2023. link

 

Macfarlane PW et al. The Early Repolarization Pattern: A Consensus Paper. J Am Coll Cardiol. 2015;66(4):470-7.

PMID: 26205599 DOI: 10.1016/j.jacc.2015.05.033

 

de Winter RJ et al. A new ECG sign of proximal LAD occlusion. N Engl J Med. 2008;359(19):2071-3.

PMID: 18987380 DOI: 10.1056/NEJMc0804737

 

de Zwaan C. Characteristic electrocardiographic pattern indicating a critical stenosis high in left anterior descending coronary artery in patients admitted because of impending myocardial infarction. Am Heart J. 1982;103:730-6.

PMID: 6121481 DOI: 10.1016/0002-8703(82)90480-x

 

Brady WJ et al. High-risk electrocardiogram presentations in the acute coronary syndrome patient - Beyond ST-segment elevation myocardial infarction. Turk J Emerg Med. 2025;25(1):1-9.

PMID: 39882089 DOI: 10.4103/tjem.tjem_150_24

 

Deshpande A & Birnbaum Y. ST-segment elevation: Distinguishing ST elevation myocardial infarction from ST elevation secondary to nonischemic etiologies. World J Cardiol. 2014;6(10):1067-79.

PMID: 25349651 DOI: 10.4330/wjc.v6.i10.1067

 

Lowenstein SR (2018). Critical Cases in Electrocardiograpy. Cambridge University Press, UK.

 

Lester RM & Paglialunga S. Surfing the T Wave: A Primer on ECG T Wave Morphologies Encountered in Clinical Trials and Impact on the QT Interval and Patient Safety. Clin Transl Sci. 2025 Mar;18(3):e70145.

PMID: 40120141DOI: 10.1111/cts.70145

 

Brieger DB et al. National Heart Foundation of Australia and Cardiac Society of Australia and New Zealand: Australian Clinical Guideline for Diagnosing and Managing Acute Coronary Syndromes 2025. Med J Aust. 2026;224(2):e70127.

PMID: 41693087 DOI: 10.5694/mja2.70127

 

Herman R et al. AI-Enabled ECG Analysis Improves Diagnostic Accuracy and Reduces False STEMI Activations: A Multicenter U.S. Registry. JACC Cardiovasc Interv. 2026;19(2):145-156.

PMID: 41158088 DOI: 10.1016/j.jcin.2025.10.018

 

Grautoff S. STEMI Equivalent in Ventricular Pacemaker Rhythm. Dtsch Arztebl Int. 2018;115(41):686.

PMID: 30406754 DOI: 10.3238/arztebl.2018.0686

 

 

 

 

 

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Credit Designation Statement

AMA Physician’s Recognition Award

Acadoodle, Ltd designates this enduring material activity for a maximum of 2.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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